The O authors O describe O the O case O of O a O 56 O year O old O woman O with O chronic O , O severe O heart O failure O secondary O to O dilated O cardiomyopathy O and O absence O of O significant O ventricular O arrhythmias O who O developed O QT O prolongation O and O torsade O de O pointes O ventricular O tachycardia O during O one O cycle O of O intermittent O low O dose O ( O 2.5 O mcg O / O kg O per O min O ) O dobutamine O . O This O report O of O torsade O de O pointes O ventricular O tachycardia O during O intermittent O dobutamine O supports O the O hypothesis O that O unpredictable O fatal O arrhythmias O may O occur O even O with O low O doses O and O in O patients O with O no O history O of O significant O rhythm O disturbances O . O The O mechanisms O of O proarrhythmic O effects O of O Dubutamine O are O discussed O . O